Abstract
The present work aimed to study the current situation of antibiotic resistance of human pathogens caused Urinary tract infection (UTI). 100 urine samples were collected from patients ranging the age from 5 to 70 years. Bacterial pathogens were isolated and identified following the definition of the National Committee of Clinical Laboratory Standards. The obtained results showed that Escherichia coli was the predominant pathogen (48%) causing UTI, followed by Klebsiella pneumoniae (19%), Pseudomonas aeruginosa (6%), Proteus mirables (6%), Enterobacter cloacae (4%), Enterococcus faecalis (4%), Citrobacter koseri (2%), Staphylococcus aureus (1%), Acintobacter beun (1%), Staphylococcus sciuri (1%), Serratia marcescens (1%) and negative samples (5%). Strains isolated from urinary tract infections were examined for susceptibility to antibiotics, few of antibiotics were effective and most of pathogens were resistant and were grouped as multidrug resistant (MDR) strains. Among this E. coli, K. pneumoniae and P. aeruginosa were highly resistant to the antibiotics, whereas Staphylococus and Serratia marcescens exhibited high sensitivity to cefoxitin, cefepime and aztreonam. The present study evaluated the prevalence of bacteria implicated in UTI and indicated the emerging of multidrug resistance among the isolated bacterial pathogens.

Key words: Urinary tract infection, antibiotics, Escherichia coli