E-ISSN 2090-0503 | ISSN 1687-7497
 
2023, Vol: 19, Issue: 2
19 / 2Current Issue Online FirstArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles

Original Research 


EXTENDED-SPECTRUM β-LACTAMASE PRODUCING ESCHERICHIA COLI AND KLEBSIELLA PNEUMONIAE IN URINARY TRACT INFECTIONS

Elsawy Essam Elkady I. Mohamed El-Masry S. Ali Ahmed Y. Farg.

Abstract
Bacterial species were isolated from clinical urinary specimens from hospitalized patients by urinary tract infections using standard microbiological procedures. The identification to the species level and antimicrobial susceptibility test has been carried out by automated method with Vitek 2 system (bioMérieux, Marcy L’Etolile, France). Production of ESBL activity was confirmed in screening-positive isolates via a double-disk synergy test. CTX-M type ESBLs was screened in isolates of E. coli and Klebsiella pneumoniae. The results showed that the prevalence of ESBL producers was very high up to 70% (49 of 70) among E. coli isolates and 68.8% (11 of 16) among K. pneumoniae. Resistance rates of E. coli isolates ESBL producers is 90 % for Amoxicillin/clavulanate, 86% for Trimethoprim-sulfamethoxazole & Ciprofloxacin, 49% for Nitrofurantoin ,18% for Piperacillin/tazobactam and 2% for Imipenem & Amikacin . In K. pneumoniae ESBL producers isolates resistance rate is 91% for Nitrofurantoin, 73% for Amoxicillin/clavulanate, 64% for Ciprofloxacin & Trimethoprim-sulfamethoxazole and 18% for Piperacillin/ tazobactam. Polymerase chain reaction detected blaCTX-M in 42 of 70 (60 %) of E. coli and 5 of 16 (31%) of K. pneumoniae isolates. These bacteria demonstrated a significant increase in resistance rates to several non-β-lactam antibiotics and expressed a multidrug resistance phenotype at a high rate. This study poses a serious concern for infection control in Urology & Nephrology Center and indicates the need for immediate action to prevent further spread of these resistant bacteria.

Key words: ESBL, E. coli, Klebsiella pneumoniae, blaCTX-M.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Elsawy Essam Elkady I. Mohamed El-Masry S. Ali Ahmed Y. Farg
on Google
on Google Scholar

How to Cite this Article
Pubmed Style

Elsawy Essam Elkady I. Mohamed El-Masry S. Ali Ahmed Y. Farg. EXTENDED-SPECTRUM β-LACTAMASE PRODUCING ESCHERICHIA COLI AND KLEBSIELLA PNEUMONIAE IN URINARY TRACT INFECTIONS. Egypt. J. Exp. Biol. (Bot.). 2011; 7(1): 135-141.

Web Style

Elsawy Essam Elkady I. Mohamed El-Masry S. Ali Ahmed Y. Farg. EXTENDED-SPECTRUM β-LACTAMASE PRODUCING ESCHERICHIA COLI AND KLEBSIELLA PNEUMONIAE IN URINARY TRACT INFECTIONS. https://www.egyseb.net//?mno=186937 [Access: December 06, 2023].

AMA (American Medical Association) Style

Elsawy Essam Elkady I. Mohamed El-Masry S. Ali Ahmed Y. Farg. EXTENDED-SPECTRUM β-LACTAMASE PRODUCING ESCHERICHIA COLI AND KLEBSIELLA PNEUMONIAE IN URINARY TRACT INFECTIONS. Egypt. J. Exp. Biol. (Bot.). 2011; 7(1): 135-141.


Vancouver/ICMJE Style

Elsawy Essam Elkady I. Mohamed El-Masry S. Ali Ahmed Y. Farg. EXTENDED-SPECTRUM β-LACTAMASE PRODUCING ESCHERICHIA COLI AND KLEBSIELLA PNEUMONIAE IN URINARY TRACT INFECTIONS. Egypt. J. Exp. Biol. (Bot.). (2011), [cited December 06, 2023]; 7(1): 135-141.


Harvard Style

Elsawy Essam Elkady I. Mohamed El-Masry S. Ali Ahmed Y. Farg (2011) EXTENDED-SPECTRUM β-LACTAMASE PRODUCING ESCHERICHIA COLI AND KLEBSIELLA PNEUMONIAE IN URINARY TRACT INFECTIONS. Egypt. J. Exp. Biol. (Bot.), 7 (1), 135-141.


Turabian Style

Elsawy Essam Elkady I. Mohamed El-Masry S. Ali Ahmed Y. Farg. 2011. EXTENDED-SPECTRUM β-LACTAMASE PRODUCING ESCHERICHIA COLI AND KLEBSIELLA PNEUMONIAE IN URINARY TRACT INFECTIONS. THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Botany), 7 (1), 135-141.


Chicago Style

Elsawy Essam Elkady I. Mohamed El-Masry S. Ali Ahmed Y. Farg. "EXTENDED-SPECTRUM β-LACTAMASE PRODUCING ESCHERICHIA COLI AND KLEBSIELLA PNEUMONIAE IN URINARY TRACT INFECTIONS." THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Botany) 7 (2011), 135-141.


MLA (The Modern Language Association) Style

Elsawy Essam Elkady I. Mohamed El-Masry S. Ali Ahmed Y. Farg. "EXTENDED-SPECTRUM β-LACTAMASE PRODUCING ESCHERICHIA COLI AND KLEBSIELLA PNEUMONIAE IN URINARY TRACT INFECTIONS." THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Botany) 7.1 (2011), 135-141. Print.


APA (American Psychological Association) Style

Elsawy Essam Elkady I. Mohamed El-Masry S. Ali Ahmed Y. Farg (2011) EXTENDED-SPECTRUM β-LACTAMASE PRODUCING ESCHERICHIA COLI AND KLEBSIELLA PNEUMONIAE IN URINARY TRACT INFECTIONS. THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Botany), 7 (1), 135-141.


Author LoginReviewer LoginAbout PublisherEditorial PoliciesEditorial Review PolicyPeer Review PolicyEditorial & Peer Review ProcessPublication Ethics and Publication Malpractice StatementConflict of Interest PolicyPlagiarism PolicyProtection of Research Participants (Statement On Human And Animal Rights)Privacy PolicySelf-Archiving PoliciesTerms of UseLicense Information

About THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Botany)

The Egyptian Journal of Experimental Biology (Botany) publishes original scientific research concerning botanical sciences (Morphology, Taxonomy, Gen ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information

egysebbz@gmail.com